Ammonia Affects Astroglial Proliferation in Culture.
Primary cultures of rat astroglial cells were exposed to 1, 3 and 5 mM NH4Cl for up to 10 days.Dose- and time-dependent reductions in cell numbers were seen, plus an increase in the proportion of cells in the S phase.The DNA content was reduced in the treated cells, and BrdU incorporation human after all vinyl diminished.However, neither ammonia no